abstract：:Schwann cells (SC), the glial cells of peripheral nerves, are involved in many diseases including Charcot Marie Tooth and neurofibromatosis, and play a pivotal role in peripheral nerve regeneration. Although it is possible to obtain human SC from nerve biopsies, they are difficult to maintain and expand in culture. He...

journal_title：Stem cell reviews and reports

authors： Ziegler L,Grigoryan S,Yang IH,Thakor NV,Goldstein RS

更新日期：2011-06-01 00:00:00

abstract：:Although the stem cells are commonly isolated by FACS or MACS, they are very expensive and these is no specific marker for liver stem/progentior cells (LSPCs). This paper applied a convenient and efficient method to enrich LSPCs. The fetal liver cells (FLCs) were firstly enriched by Percoll discontinuous gradient cent...

journal_title：Stem cell reviews and reports

authors： Liu WH,Li R,Dou KF

更新日期：2011-03-01 00:00:00

abstract：:The ROCK inhibitor Y-27632 inhibits apoptosis and increases proliferation of frozen-thawed cells. We examined the role of Y-27632 on human umbilical cord Wharton's jelly stem cells (hWJSCs) for (1) thaw-survival (2) proliferation and (3) preservation of stemness and differentiation potential after cryopreservation. hW...

journal_title：Stem cell reviews and reports

authors： Gauthaman K,Fong CY,Subramanian A,Biswas A,Bongso A

更新日期：2010-12-01 00:00:00

abstract：:Cerebral ischemia induces death of all neural cell types within the region affected by the loss of blood flow. We have shown that administering human umbilical cord blood cells after a middle cerebral artery occlusion in rats significantly reduces infarct size, presumably by rescuing cells within the penumbra. In this...

journal_title：Stem cell reviews and reports

authors： Jiang L,Saporta S,Chen N,Sanberg CD,Sanberg P,Willing A

更新日期：2010-12-01 00:00:00

abstract：:Human embryonic stem cells (hESCs) are especially resistant to several cellular stresses, but the existence and induction of Endoplasmic Reticulum (ER) stress by culture conditions are unknown. Using qPCR, here, we investigated the behavior of the principal sensors of ER stress and their relation with the feeder layer...

journal_title：Stem cell reviews and reports

authors： Blanco-Gelaz MA,Suarez-Alvarez B,Ligero G,Sanchez L,Vidal-Castiñeira JR,Coto E,Moore H,Menendez P,Lopez-Larrea C

更新日期：2010-09-01 00:00:00

abstract：:Previous studies demonstrated that induced pluripotent stem (iPS) cells could produce viable mice through tetraploid complementation, which was thought to be the most stringent test for pluripotency. However, these highly pluripotent iPS cells were previously reported to be generated from fibroblasts of embryonic orig...

journal_title：Stem cell reviews and reports

authors： Zhao XY,Li W,Lv Z,Liu L,Tong M,Hai T,Hao J,Wang X,Wang L,Zeng F,Zhou Q

更新日期：2010-09-01 00:00:00

abstract：:Xenografting of normal and transformed mammalian tissues and cells to chick embryos has been performed for almost 100 years. Embryonic stem cells, derived more than 25 years ago from murine, and more than 10 years ago from human blastocysts, have transformed many fields of biological research. There is a growing body ...

journal_title：Stem cell reviews and reports

authors： Goldstein RS

更新日期：2010-09-01 00:00:00

abstract：:The morphology of several tumors mimics developmentally early tissues; tumors often express early developmental markers characteristic for the germ line lineage. Recently, our group identified a population of very small stem cells (SCs) in murine bone marrow (BM) and other adult organs that express several markers cha...

journal_title：Stem cell reviews and reports

authors： Ratajczak MZ,Shin DM,Liu R,Marlicz W,Tarnowski M,Ratajczak J,Kucia M

更新日期：2010-06-01 00:00:00

abstract：:Few surface markers are available to monitor lineage differentiation during chondrogenesis. Recently, delta-like1/fetal antigen1 (dlk1/FA1), a transmembrane protein of the Notch/Delta/Serrata family, was shown to be essential for inducing early chondrogenesis. Thus, we investigated the possible use of dlk1/FA1 as a no...

journal_title：Stem cell reviews and reports

authors： Harkness L,Taipaleenmaki H,Mahmood A,Frandsen U,Saamanen AM,Kassem M,Abdallah BM

更新日期：2009-12-01 00:00:00

abstract：:Since its early days, stem cell research, particularly human embryonic stem cell research, has been the focus of intense social debate, and the question of the moral status of the embryo has been a central issue in the controversy. Despite this friction, and while it has yet to obtain widespread success in clinical ap...

journal_title：Stem cell reviews and reports

authors： Zarzeczny A,Caulfield T

更新日期：2009-06-01 00:00:00

abstract：:The model of cancer stem cells in tumor development states that tumors contain a subset of cells that both self renew and give rise to differentiated progeny. Like normal adult tissue stem cells, cancer stem cells are a minority of the whole tumor and are the only cells that are able to maintain tumor growth indefinit...

journal_title：Stem cell reviews and reports

authors： La Porta C

更新日期：2009-03-01 00:00:00